Artificial intelligence (AI) is a disruptive technology in the business realm with transformational impact. From detecting malware and preventing money laundering, to automating insurance claims and optimizing inventory and improving product recommendations, and more — AI will continue to necessitate changes in core business processes and models. Within the past few years, machine learning, while not fully tapped in the business sphere, has become more effective and widely utilized. Tomorrow’s leaders and managers will need to integrate machine learning where appropriate, incorporating its capabilities with those of humans. The design and implementation of new combinations of technologies with human skills to meet customers’ needs will require critical thinking skills, creativity, and project planning.